ea0024oc1.5 | Oral Communications 1 | BSPED2010
Thankamony A
, Jensen R B
, O'Connell S
, Kirk J M W
, Donaldson M D C
, Ivarsson Sten-A
, Soder O
, Hoey H
, Juul A
, Dunger D B
Background: Individuals born Small for Gestational age (SGA) are at high risk of development of type 2 diabetes. Growth hormone (GH) therapy can also adversely affect glucose metabolism.Aim: To explore the factors associated with changes in insulin sensitivity (IS) and insulin secretion during one year of GH treatment in children born SGA.Methods: In the NESGAS clinical trial, we studied 82 (55♂) pre-pubertal children (age 3....